Dynamometer

The wattmeter is an electrodynamic instrument for measuring the electric power or the supply rate of electrical energy of any given circuit. The device consists of a pair of fixed coils, known as current coils, and a movable coil known as the potential coil. The current coils are connected in series with the circuit, while the potential coil is connected in parallel. Also, on analog wattmeters, the potential coil carries a needle that moves over a scale to indicate the measurement. A current flowing through the current coil generates an electromagnetic field around the coil. The strength of this field is proportional to the line current and in phase with it. The potential coil has, as a general rule, a high-value resistor connected in series with it to reduce the current that flows through it. The result of this arrangement is that on a dc circuit, the deflection of the needle is proportional to both the current and the voltage, thus conforming to the equation W=VA or P=EI. On an ac circuit the deflection is proportional to the average instantaneous product of voltage and current, thus measuring true power, and possibly (depending on load characteristics) showing a different reading to that obtained by simply multiplying the readings showing on a stand-alone voltmeter and a stand-alone ammeter in the same circuit. The two circuits of a wattmeter are likely to be damaged by excessive current. The ammeter and voltmeter are both vulnerable to overheating – in case of an overload, their pointers will be driven off scale – but in the wattmeter, either or even both the current and potential circuits can overheat without the pointer approaching the end of the scale! This is because the position of the pointer depends on the power factor, voltage and current. Thus, a circuit with a low power factor will give a low reading on the wattmeter, even when both of its circuits are loaded to the maximum safety limit. Therefore, a wattmeter is rated not only in watts, but also in volts and amperes. Retrieved from â€Å"http://en. wikipedia. org/wiki/Wattmeter† (A dynamometer consists of an absorption (or absorber/driver) unit, and usually includes a means for measuring torque and rotational speed. An absorption unit consists of some type of rotor in a housing. The rotor is coupled to the engine or other equipment under test and is free to rotate at whatever speed is required for the test. Some means is provided to develop a braking torque between dynamometer's rotor and housing. The means for developing torque can be frictional, hydraulic, electromagnetic etc. according to the type of absorption/driver unit. One means for measuring torque is to mount the dynamometer housing so that is free to turn except that it is restrained by a torque arm. The housing can be made free to rotate by using trunnions connected to each end of the housing to support the dyno in pedestal mounted trunnion bearings. The torque arm is connected to the dyno housing and a weighing scales is positioned so that it measures the force exerted by the dyno housing in attempting to rotate. The torque is the force indicated by the scales multiplied by the length of the torque arm measured from the center of the dynamometer. A load cell transducer can be substituted for the scales in order to provide an electrical signal that is proportional to torque. Another means for measuring torque is to connect the engine to the dynamometer through a torque sensing coupling or torque transducer. A torque transducer provides an electrical signal that is proportional to torque. With electrical absorption units, it is possible to determine torque by measuring the current drawn (or generated) by the absorber/driver. This is generally a less accurate method, but it may be adequate for some purposes. A wide variety of tachometers are available for measuring speed. Some types can provide an electrical signal that is proportional to speed. When torque and speed signals are available, test data can be transmitted to a data acquisition system rather than being recorded manually. Speed and torque signals can also be recorded by a chart recorder or plotter. ) Power in an electric circuit is the product (multiplication) of voltage and current, so any meter designed to measure power must account for both of these variables. A special meter movement designed especially for power measurement is called the dynamometer movement, and is similar to a D'Arsonval or Weston movement in that a lightweight coil of wire is attached to the pointer mechanism. However, unlike the D'Arsonval or Weston movement, another (stationary) coil is used instead of a permanent magnet to provide the magnetic field for the moving coil to react against. The moving coil is generally energized by the voltage in the circuit, while the stationary coil is generally energized by the current in the circuit. A dynamometer movement connected in a circuit looks something like this: [pic] The top (horizontal) coil of wire measures load current while the bottom (vertical) coil measures load voltage. Just like the lightweight moving coils of voltmeter movements, the (moving) voltage coil of a dynamometer is typically connected in series with a range resistor so that full load voltage is not applied to it. Likewise, the (stationary) current coil of a dynamometer may have precision shunt resistors to divide the load current around it. With custom-built dynamometer movements, shunt resistors are less likely to be needed because the stationary coil can be constructed with as heavy of wire as needed without impacting meter response, unlike the moving coil which must be constructed of lightweight wire for minimum inertia.

Martin Luther King Jr Essay

In 1998, an Atlanta Federal District Court judge ruled that Martin Luther King’s â€Å"I Have a Dream† speech was part of national history and that CBS did not need to seek permission to air it in an historical documentary that included a segment on the civil rights movement. The documentary, broadcast in 1994, incorporated a nine-minute excerpt of King’s historic speech. The King Corporation lawyers in the case argued that CBS had unlawfully used King’s â€Å"eloquent, creative, literary expressions. Arguing the decision before the 11th Circuit Court of Appeals, the King family succeeded in having it overturned two years later. Although the decision was the first to legally cement the King family’s rights, this was not the first time the copyright had become an issue, nor would it be the last. Presciently, King had copyrighted the speech a month after it was delivered and his heirs clung tenaciously to the idea that it was a bequest to them (Stout 16). Clarence Jones, King’s lawyer and confidant, filed suit against Twentieth Century Fox Records and Mr.  Maestro Records for issuing bootleg copies of the speech (Branch 886). However, King granted Motown Records permission to release two recordings of his speeches (â€Å"Great March to Freedom† and â€Å"Great March to Washington†), but told Motown founder Berry Gordy that he wanted the entire proceeds to be donated to the Southern Christian Leadership Conference (SCLC). When Gordy urged King to keep half of the royalties for himself and his family, King insisted it go to the SCLC so as not to give the impression that he was benefitting from the cause of civil rights (Posner 175–76). King’s family, like Gordy, has seen the speech as an important source of revenue, some of which undoubtedly has been used to promote King’s legacy. Since winning their appeal against CBS, the King family has continued to exploit the copyright of the speech, agreeing to sell the French telephone company Alcatel the right to use a digitally altered version of the event for a 2001 television commercial. The commercial 184 Martin Luther King Jr. ’s â€Å"I Have a Dream† Speech 185 shows King speaking jarringly absent the 250,000 people who had on that day lined the reflecting pool on the national mall. The commercial asks what would have happened if King’s words had not been able to â€Å"connect† with his audience (Szegedy-Maszak 20). Selling a permission to use the speech for a television commercial and engaging in legal wrangling about the news media’s right to rebroadcast the speech are not developments that could be predicted from the iconic status the speech has achieved in national history. Although the legal dimensions of the speech’s dissemination are of interest, we are primarily interested in how King’s speech has become a permanent fixture in the collective memory of American citizens despite the copyright controversy. In a recent book on the speech, Drew Hansen suggests that it is â€Å"the oratorical equivalent of the Declaration of Independence† (The Dream 214). What Edwin Black said of the Gettysburg Address is equally true of â€Å"I Have a Dream†: â€Å"The speech is fixed now in the history of a people† (Black 21). Far more than an ordinary written or performed text, King’s speech is now viewed as a text belonging to the nation, despite its current legal status. Coretta Scott King suggested that when King delivered the speech he was â€Å"connected to a higher power† (King). Whether or not divinely inspired, the speech has come to symbolize the civil rights movement and anchors collective public memory of the 1963 March on Washington for Jobs and Equality and of King himself. Although King’s â€Å"I Have a Dream† speech is now recognized as one of the most important speeches of the twentieth century, this has not always been the case. Reactions to the speech immediately following its delivery were mixed. Some praised the speech, while inexplicably others completely ignored it. How did King’s speech achieve its iconic status given the mixed reaction immediately following its presentation? Thinking of the speech as generative of its own fame supports the legendary aura that now surrounds it, but its elevated stature resulted from a gradual process of media dissemination and cultural amplification. The touchstones in this process included eventual comparisons of King’s rhetoric to Lincoln’s, media portrayals of King’s role in the civil rights movement following his assassination, and the appropriation of the speech as a synecdoche for that movement. The memory of Lincoln’s speech was fixed by print, while King’s speech was fixed by the electronic media. In 1863, no one realized that Abraham Lincoln’s humble â€Å"Remarks by the President† at the Gettysburg ceremony would have become part of national iconography. Years later, Carl Sandburg referred to it reverentially as the â€Å"great American poem,† but part of the apocryphal lore of the speech is that Lincoln truly believed the world would not â€Å"note nor long remember† what he and others said at Gettysburg. Senator Edward Everett, one 186 ANQ: A Quarterly Journal of Short Articles, Notes, and Reviews of the great ceremonial orators of his day, had satisfied every expectation of his audience with an address that took him two hours to deliver. It had taken Lincoln only three minutes to utter his 272 words (Wills 68). Lincoln’s speech gradually reached a secondary audience through the accounts of newspapers; King’s speech was instantaneously heard and seen by radio listeners and television viewers numbering in the millions. For all its compelling metaphor and soaring imagery, â€Å"I Have a Dream† is more drama than poetry; as drama, it must be heard and seen. King’s rhetorical genius was oral, Lincoln’s written. Lincoln spoke transcendentally, while King spoke in the moment. Journalist Richard Carter, an eyewitness of the speech, reminds us that never before had a civil rights demonstration been aired live on national television (38). It was also the last such mass meeting to be broadcast (Branch 876). Of the ten civil rights leaders who spoke at the rally, King did most to ignite the crowd, but the impact on television audiences derived from the interplay of King, his speech, the response of the crowd, and even the frequent cutaways to Lincoln’s statue. Carter finds it â€Å"inexplicable† that television critic Kay Gardella of the New York Daily News, who acknowledged that the speech was the most moving of the rally, subordinated the impress of King’s words to the visual images that the television camera associated with them: â€Å"Most effective and meaningful,† she aid, â€Å"were the cutaways to Lincoln’s statue† (38). To those in the television medium who recorded the speech, and probably to those who watched it, the stone statue of the Great Emancipator amplified the combined effect of King’s lyrical words, mellifluous voice, and determined countenance. The symbolic interplay between King and Lincoln was also not lost on E. W. Kenworthy, who filed the front page story for the Times: â€Å"It was Dr. King—who had suffered perhaps most of all—who ignited the crowd with words that might have been written by the sad brooding man enshrined within† (1). James Reston, on the same New York Times front page, declared that King â€Å"touched the vast audience. Until then the pilgrimage was merely a great spectacle† (1). The Time Magazine article about the rally clearly understood the importance of King’s speech: â€Å"King’s particular magic had enslaved his audience,† Time said of the prepared portion of King’s text, while particularly praising the extemporized section with which the speech ended as â€Å"catching, dramatic, inspirational† (â€Å"Beginning†). Not every major news outlet recognized the importance of King’s speech. The Washington Post, for example, focused on the speech delivered by A. Philip Randolph, without even mentioning King’s (Branch 886). The historic and literary brilliance of Lincoln’s address at Gettysburg had also not been universally recognized by journalists. The fact that Lincoln’s speech became so famous is doubly remarkable when one considers how few people actually heard it or saw so much as a photograph of Lincoln delivering it. Illustrators would fill in the visual gaps that photographers likeMatthew Brady had left out. There is Martin Luther King Jr. s â€Å"I Have a Dream† Speech 187 only one photograph of Lincoln on the speaker’s platform and it was taken from some distance away (Kunhardt, Kunhardt, and Kunhardt 315). King’s speech, by contrast, was forever wedded to a set of visual images—of Lincoln’s statue, of the responsive throng, and of King himself, visibly moved by his own words. It is difficult to explain precisely how King’s speech went from privately copyrighted words to cherished public property, but surely the number of people who saw and heard and felt his speech live was an important ingredient. In the case of Lincoln’s speech, it helped that it was apparently spare and simple, something school children could easily read, memorize, and declaim. At eighteen minutes, King’s speech is roughly six times as long as Lincoln’s, but the dramatic climax of the speech is short enough to replay in honoring King or in the retelling of civil rights movement history, and the imagery of the speech is often striking. Both King’s and Lincoln’s speeches were tied to a momentous event, and the messages of both can be appreciated, if not fully understood, by successive generations without providing detailed historical context. The same cannot be said of Lincoln’s lawyerly and highly nuanced First Inaugural Address, or for that matter King’s Vietnam era antiwar speech, â€Å"A Time to Break Silence. † The addresses at Gettysburg and the Lincoln Memorial abridge tumultuous chapters in American history. Martyrdom, Memorialization, and Mass Circulation The martyrdom of Lincoln and King did much to propel rehearsals of their deeds and words. Pulitzer Prize winning historian David Garrow agrees with King biographer Drew Hansen that the speech received little further mention until after King was assassinated. Although King was honored by Time as its Man of the Year in 1964, the same year he won the Nobel Peace Prize, prior to King’s assassination there was not a reason for the press to commemorate King’s biography or place in history. The identification between King and his enunciated â€Å"dream† heard by millions was unavoidable and seemingly inevitable. Soon after his death, Motown Records reissued a single recording of the â€Å"Dream† speech (Waller 48). Eulogizing King in 1968, Time spoke of the â€Å"dream† peroration of his speech as the peak of his oratorical career (â€Å"Transcendent†). While Corretta King asked supporters to â€Å"join us in fulfilling his dream† (Rugaber 1), the New York Times structured its eulogy of â€Å"the fallen martyr† by discussing aspects of his â€Å"dream† (â€Å"He had a dream† E12), and in another article judged that his speech at the LincolnMemorial was â€Å"the high point of Dr. King’s war for civil rights† (Mitgang E1). King himself perpetuated his identification with â€Å"the dream† by introducing it into his later speeches. 188 ANQ: A Quarterly Journal of Short Articles, Notes, and Reviews Immediately after the assassination, Democratic Congressmen proposed the establishment of a Martin Luther King Jr. oliday, but it did not come to fruition until 1983 (Hansen, The Dream 216). The holiday itself has given impetus for annual memorializing of King and synoptic renderings of his life. Thus, the speech, particularly the prophetic â€Å"dream† section and dramatic conclusion, continued to be heard by virtually every generation of Americans. The speech was widely anthologized and was so widely taught in college public speaking classes that in 1982 Haig Bosmajian published an article in Communication Education to correct inaccurate versions of the speech. In 1998, Time listed it as one of only four of the â€Å"century’s greatest speeches,† putting the speech in a firmament with speeches by Churchill, Roosevelt, and Kennedy and offering an abbreviated quotation of the â€Å"dream† section and peroration (â€Å"Four†). Within recent years, two books have been written about the speech, as books were also written about the Gettysburg address (Sunnemark; Hansen, The Dream). There are few American speeches so important as to inspire book-length treatments. The anointing of the speech by the media has been a mixed blessing. Historians and civil rights proponents caution against the condensation of a rich life into a single event. King’s later speeches, which include continued references to his dream, proved less successful in the North than they had been in the South. â€Å"I have felt my dreams falter,† he said in Chicago in 1965, and on Christmas Eve 1967, reflecting on his own life, he added a dream reference made famous by poet Langston Hughes: â€Å"I am personally the victim of deferred dreams, of blasted hopes. In his final years, the sweeping imagery of his famous 1963 speech gave way to a more focused advocacy on behalf of African Americans in their struggles for jobs, higher salaries, better working conditions, and integration (Hansen, â€Å"King’s Dreams† E11). King also adamantly opposed the VietnamWar and called for a guaranteed family income. Worried about the dissolution of the civil rights movement, he argued for a more aggressive and disruptive brand of nonviolence, threatened boycotts, and even suggested obstructing the national Democratic and Republican conventions (â€Å"Transcendent†). Because King’s rhetoric is defined by the celebrated dream speech, his later speeches, which do not fit this model, are relatively unremembered. How much â€Å"I Have a Dream† has come to represent Martin Luther King is revealed by the planned national memorial in Washington, DC, for which ground was recently broken. Situated between the Lincoln and Jefferson Memorials, the Martin Luther King Memorial will include structures and elements that materially evoke King’s speeches, particularly â€Å"I Have a Dream. Clayborne Carson, the director of the King Paper’s Project at Stanford University, offered suggestions for the design selected from among more than 900 submissions. He proposed that King’s public words be used as inspiration for the structures in the open-air Martin Luther King Jr. ’s â€Å"I Have a Dream† Speech 189 memorial. Thus the features of the memorial include a â€Å"mountain of despair† and a â€Å"stone of hope,† reflecting a phrase from the speech. There is a fountain meant to symbolize the biblical quotation King used in the speech, the passage that â€Å"Justice rolls down like water and righteousness like a mighty stream. There are naves, representing the leaders of the civil rights movement, â€Å"hewn from rock, with rough edges on the outside, and smooth stone on the inside,† again an homage to a biblical passage in King’s dream speech (â€Å"The rough places shall be made plane and the crooked places shall be made straight†) (Konigsmark 1B). The importance of King’s speech in American history is also illustrated by its incorporation at the Lincoln Memorial. Visitors can watch footage of King’s speech and note the spot where King delivered the speech, which is conspicuously marked with an X. Conclusion Historical interest in how King came to include the â€Å"I have a dream† section is comparable to the interest in how Lincoln composed his Gettysburg Address, which has produced tales of fanciful composition on an envelope while en route to Gettysburg. King had been given seven minutes to deliver his speech and his prepared text fit roughly into that time limit until King departed from his text to declare that â€Å"We will not be satisfied until justice runs down like waters and righteousness like a mighty stream. The voluble affirmation from the audience made King reluctant to continue reading from his manuscript. At this crucial turn, King recast the subdued request that the attendees should â€Å"go back to our communities† with a dynamic series of imperatives: â€Å"Go back to Mississippi. Go back to South Carolina. Go back to Louisiana. Go back to the slums and ghettos of our Northern cities, knowing that somehow this situation can and will be changed. Let us not wallow in the valley of despair. † Mahalia Jackson, who had earlier sung a black spiritual, shouted from behind King: â€Å"Tell ‘em about the dream, Martin. Whether through the singer’s prompting or by his own initiative, King launched nearly seamlessly into the now famous sentences that embodied his dream (Branch 881–82). There are competing accounts of why King chose to depart from his text and prepared conclusion to improvise the â€Å"I have a dream† refrain. While Corretta said that he had considered including this section beforehand if the moment was right, in a 1963 interview King remembered that he included it on an impulse: â€Å"I just felt I wanted to use it here. I don’t know why. I hadn’t thought about it before the speech† (Hansen, The Dream). King’s version lends credence to Coretta’s idea that it was inspired by a higher power (King). Inspired prophecy should not require a prepared text, and extemporaneous speech, like the â€Å"winged words† of Homer’s heroes, is regarded as more authentic than written ones. 190 ANQ: A Quarterly Journal of Short Articles, Notes, and Reviews No one, not even King, could anticipate the place his scintillating speech would take in public memory. In 1963 King delivered 350 speeches and sermons. His message and rhetoric were often the same although the size of his audience and the amplitude of his public exposure were never so great. Of course, the speech itself is powerful and memorable, but contextual forces, including the live airing of the speech, King’s assassination, and the enactment of a national holiday celebrating King all contributed to making â€Å"I Have a Dream† a symbol of King’s life, which in turn is a symbol of the civil rights movement. It was and continues to be a media event. It expresses in shorthand the sentiments that the public is supposed to recall. What was a performed text delivered with a political purpose has been translated by the media into a symbolic narrative that casts King as the heroic voice of those for whom the dream had not yet become a reality.

The Buddha Image: A Foundation for Attachment

Madeline Brisbane Buddhism Course Assignment 11/16/11 The Buddha Image: A Foundation for Attachment According to Freedburg, the author of The Power of Images, a figure resembling human form â€Å"enables the reconstitution of life† and makes â€Å"the absent present and the dead alive† (p. 11)1. An image preserves the aura of the person it resembles, and therefore allows for an eternal essence to remain after death. Within the realm of Buddhism, images of the Buddha serve a wide variety of spiritual and practical purposes. For some, keeping a Buddha image in their home is a sign of respect.Others find it comforting and peaceful to look at a Buddha image. In some parts of the world, specifically Southeast Asia, the Buddha image is a symbol of supernatural power and protection, and is essential to the efficacy of rituals. If a ritual fails to succeed in the absence of a Buddha image, then there must be an interdependency between images and ritualistic success. And if an i nterdependency exists, then the entire concept contradicts the Buddha's teaching of non-attachment because the ritual becomes attached to the presence of a Buddha image.Through an analysis of he origins and evolution of the use of Buddha images and relics in Southeast Asia, it would appear that an obsession with the presence of a Buddha image has emerged, conflicting with Buddha's teaching about non-attachment. As the second Noble Truth states, attachment is the origin of suffering. Therefore, to foster an interdependency between images and ritualistic success would go against the most fundamental values of Buddhism.In order to maintain the most basic ideals of Buddhism, the Buddha image must only serve as a reminder of the Buddha's presence rather than s a necessary component of practicing rituals effectively. To image the Buddha is not a modern concept; the Buddha must have always been imagined through stories, myths, and symbols. However, there are many legends surrounding the or igins or the first Buddha image. The most relevant theory regarding the original Buddha image to Southeast Asia is the story of the sandalwood statue.The story appears in many Buddhist texts that emerged over time throughout Asia. Most relevant to Southeast Asia is the Pali text from Sri Lanka recounted in the Kosala-Bimba-Vannana. In ummary, the story claims that after King Pasanedi of Kosala arrived to the Jetavana monastery to visit the Buddha only to find the Buddha away on a Journey, he leaves in disappointment. He returns later and tells the Buddha that to he would like to â€Å"have an image made in the likeness of the Tathagata†¦ for the benefit of the whole world. 2 The Buddha then adds that those who build an image of the Buddha will â€Å"accrue a great, immeasurable, incalculable benefit. â€Å"3 Upon seeing the gilded, yellow- robed statue, with the Buddha's teaching inscribed into the statue, the Buddha xpands on the praiseworthy benefits ot making Buddha image s . These benefits include avoiding rebirth into Buddhist hells; being reborn into wealthy families; and eventually attaining enlightenment. Within the statue, the dharma and the Buddha image are â€Å"cohesively conjoined. 4From this ancient tale, it is clear that the first Buddha image was built based on the kings desire to feel the presence of the Buddha even when he was not physically present. The need to feel the Buddha's presence has survived thousands of years, as many Buddhists still cherish the Buddha image as a reminder of his prevailing presence. Despite the non-theistic nature of early Buddhism, the dedication that followers of the path have to keeping Buddha images around illustrates that they worshipped and continue to worship the Buddha greatly.They cherish the notion of feeling the Buddha's presence at all times. The Theravada branch of Buddhism exemplifies the extent to which the Buddha's presence is valued by followers of the path. As Theravada ascended into South east Asia from Sri Lanka after the eleventh century B. C. E. , vernacular traditions ecame increasingly popular. In nature, Theravada Buddhism worships the historical model of the Buddha as a superhuman capable of miraculous deeds.Relics were therefore treasured as objects of magical power that allowed an â€Å"actual physical connection to the Buddha† because they were either part of the Buddha's body or came into physical contact with it. 5 Because it became impossible to exist in the presence of the Buddha in his physical form after his death, inserting a relic into an image became a way to restore the physical presence of the Buddha. In doing so, he image would supposedly provide protection against evil forces. However, when the Buddha image is revered for its supernatural protective strength, the Buddha image becomes a controversial concept.It seems that the more recent traditions of magical expectation and anticipation associated with Buddha images and relics has caused a shift away from the historical emphasis on the original monastic view of high moral responsibility and spiritual practice. Instead of following one's own karmic duties of doing good in order to receive good or trusting one's own ability to practice ituals successfully the old-fashioned way, the presence of the Buddha image during ritual has turned into a necessity for many Buddhists.If the presence of a Buddha image is necessary for rituals to work properly, then there has to an interdependency between the Buddha image and ritualistic success. Western scholar Donald Swearer, author of Becoming the Buddha, argues that â€Å"the Buddha must be†¦ present for the ritual to be efficacious for the dhamma to flourish, and for the sangha to prosper. † Moreover, scholar David Eckel makes the point that â€Å"people experience mental nguish when they cannot see the Buddha. 6 Wouldn't the creation of images therefore foster an attachment between humans and objects?This correlat ion between the Buddha image and the effectiveness of rituals, the dharma, and the sangha makes the Buddha image a very powerful entity. There is even an association between kings and material symbols of the Buddha, particularly relics and images. There is a Thai custom of swearing allegiance to the king in front of the Emerald Buddha image; the Buddha image can therefore be seen as a symbol of power and not Just a representation of the Buddha. Furthermore, the Buddha image is presently interpreted as a sign of respect and a way for devotees to make merit; â€Å"the Buddha's field of merit is operative†¦ hrough his continued post-Nibbana presence in his relics and images. â€Å"7 It Buddha images currently tunction as a means to validate the effectiveness of rituals and to make merit, then there is an undeniable interdependency between the Buddha image and the success of rituals as an expression of religious devotion, and therefore an attachment between the two. Due to the fa ct that non-attachment is one of the most fundamental values established ithin Buddhism, to classify the Buddha image as a necessity would be to diverge from Buddhism altogether.In simpler terms, to be dependent on the Buddha image is to form an attachment with it, and to form an attachment is to defy the basic ideals of Buddhism. Thus, the evolution of the Buddha image as a means of preserving the Buddha's presence into an entity that is necessary for the proper execution of rituals and spiritual success, then we can no longer categorize this concept as an appropriate element of Buddhism. The Four Noble truths are the essence of the Buddhist path, and to defy them is to defy Buddhism altogether.

The experience of child-soldiers upon their return in the local Essay - 1

The experience of child-soldiers upon their return in the local communities (Nepal case) - Essay Example Demobilisation is the withdrawal of soldiers from armed groups, and reintegration implies the return of soldiers to civilian life. Reintegration is usually viewed to be an indefinite economic and social mechanism that occurs in communities locally (Wessells, 2006). This essay analyses the experience of child soldiers in Nepal upon their return in the local communities. The first section explains the social and psychological issues of redistributed child soldiers, followed by an analysis of the initiatives taken by the Nepal government and other organisations to help in the process. And the final section presents suggestions for possible alternative approaches. The United Nations considers the return of child soldiers in their local communities a complicated, continuous process that necessitates substantial resources. The urgent task is finding the families of the child soldiers in order to bring them back to their families and communities (Kuper, 1997). Although this may seem easy, it is often filled with difficulties. In numerous cases, the families and communities may have been severely damaged by war, are in dismal financial condition, and cannot take care of or support returning combatants. According to Gates (2010), even though it is at t imes claimed that child soldiers must be capable of regaining their ‘lost childhood,’ this is practically unattainable. The Maoists’ practice of enlisting children for combat or military assistance is one of the most troubling realities of the civil war in Nepal. The Maoists have exploited various methods for recruiting children (e.g. use of misleading campaigns, kidnapping of children) (Aryal, 2011). At the peak of the civil war, in territories strongly ruled by Maoists, the rebels enforced a ‘one family, one child’ policy in which every family had to offer a recruit or suffer serious punishment (Human Rights Watch, 2007, p. 5). The

Politeness in english Essay Example | Topics and Well Written Essays - 4000 words

Politeness in english - Essay Example 157). The key assumption of this definition is that social friction is generally undesirable and there are several behavioral modes that have historically been gradually developed and can be adequately categorized as being polite. It is believed that if these behavioral modes are adequately applied in society, they will have the result of either preventing friction or at least minimizing its occurrence. Another definition of politeness defines it as being a strategic avoidance of any possible conflict (Watts, 2003, p. 50). Although this definition can be perceived as being concrete, a closer examination of the definition shows that politeness is something that we tend to use rationally and consciously with the sole intent of avoiding conflict.Another proposed definition of politeness defines it as being one of the various constraints of human interaction that is primarily used to aid in the promotion of rapport, the consideration of other’s feelings and the establishment of mu tual comfort (Locher, 2004, p. 76). This definition of politeness equates politeness with a general constraint on human interaction that mainly involves a social injunction preventing one form doing the opposite (Bax and Ka?da?r 106-107). Defining politeness as being either a constraint or a set of various constraints is seen to conveniently help lead us away from any form of objectivist approach to politeness. This is mainly due to the nature of constraints that requires people to learn them on an individual basis through their social interactions and practice. Although researchers can be able to observe the various instances of emergent social practice, they are however unable to adequately observe the constraint itself (Bax and Ka?da?r 106-107). Politeness is found to be a common word that is frequently in everyday use in the English language and has various translations in different languages such as politesse in French and beleefdheid in Dutch. The tem is found to be particular ly established in most scholarly works on pragmatics and linguistics. As is common with most everyday English expressions, politeness is found to be rather fuzzy and hence its susceptibility to having multiple variations based on personal, historical and social differences. It is common for such common terms to often have wider applications than technical terms in the language and there is a tendency for uncertainty to arise in the event that the two happen to be confused. Technical terms are found to often be not everyday expressions and as such have more a generally more specific denotation. This makes it important to clearly distinguish between the basically technical term â€Å"politeness† and the more everyday notion that the term is put to use(Gotti, Dossena&Dury, 2008, p. 5). An analysis of the term politeness as it is used in these contexts can be perceived to be a very worthwhile research both historically and in the different varieties of PDE. This can have the bene fit of providing an ethnographic view of how the different speakers of the English language talk about politeness and the semantics of the word politeness or polite at several different points in the history of the English language (Gotti, Dossena&Dury, 2008, p. 5). Politeness in the English Language The distinction existing between negative and positive politeness that was

Business Marketing Essay Example | Topics and Well Written Essays - 1000 words - 1

Business Marketing - Essay Example The web sites chosen are the online book stores of firstandecond.com, amazon.com, barnesandnoble.com, and oxfordbookstore.com. These web sites have been chosen as to provide a wider perspective of online stores, since it incorporates the pioneer and the leader of online book stores amazon.com, a large publishing house in Barnes and Noble, a medium online retailer in Oxford Books, and a small book reseller in firstandsecond.com. The diversification of product range in the website of Amazon.com is wide, so that the website no longer resembles an online book seller, but an online store that caters to books, entertainment products and a range of other products. In a similar manner there is product diversification with Barnes and Noble into entertainment products. On the other hand there is no product diversification with Oxford Books and firstandsecond.com. Due to the product diversification in with Amazon.com and Barnes and Noble, there is more clustering in the main page of the website, and so the design of the website Oxford Books or firstansdsecond.com for product display is more suitable for the web site to be developed. In both these sites the central section of the first page carries product promotion message and below that are clear images of the products on offer, with a peel in facility for more details on the products, which includes the price. This enables a customer to get more information on the range of products available before exercising a buy option. On the left are options that enable a customer to gain more insight into the company, its history and policies and the like. On the right side of the first page are promotion information like promotional offers on products, new arrivals and specific topics on which books are available. In all these web sites the option for multiple purchases exists and so there is a shopping cart to which the products chosen can be added and the list of

Gambling in Australia Essay Example | Topics and Well Written Essays - 750 words

Gambling in Australia - Essay Example This has impacted on families, government, the society and employee, due to the addiction provided by the gambling activities. To control the gambling activities in Australia, states have been passing legislations that are aimed at regulating the gaming activities. The Papua New Guinea in 2007 passed one of these resolutions aimed at regulating land based and online gaming activities. This regulation was aimed at granting casino license to any gambling service provider based in Australia or foreign (Diaconu, 2010). The Vanuatu parliament had enacted such regulations in 2000, seeking to limit the players’ age limit and controlling the gaming activities through strict control of the gambling criteria. The problem of alcohol intake and smoking has been that as passive gaming increases, the rate at which the gamers smoke and take alcohol drastically increase. The drug addiction has led the Australian Gaming Council to undertake initiatives of sensitizing the gamers concerning resp onsible gaming activities (Australian Gaming Council, 2008). According to Fabianson (2010), the gambling activities and the alcohol related intake in passive gaming have been on the rise in low level education class of people, with males dominating the gaming activities. ... The Australian National Drugs Strategy, ANDS argues that gambling has resulted to increased rates of social problems. Gambling as the ANDS elaborates affects a larger population than the individual and pathological gambling is listed as an impulsive control disorder. The disorders are driven by the arousal, pleasure and gratification. The ANDS report elaborates that recurrent gambling behavior that leads to addiction results to significant disruptions in family, personal, vocational, social lives. The compulsive behavior has resulted to job losses as employees are addicted, and they have to take the gaming activity to fulfill the string desired in gambling addiction. This is aggravated by the heavy drugs intake that results from the passive gaming activities, and has exposed many gamers to health risks (Diaconu, 2010). The Australian gambling sector has however been instrumental to the economy of the country despite the social impact it has created. It is estimated that in 2001-2002 Australians gambled away AUD 13.8 billion (Clark, Cho & Hoyler, 2010). The gambling industry created more than 9000 new jobs in three years from 2001, and as Fabiasnson (2010) argues, gambling has been a good source of income to the government through heavy taxation, and other levies that result from gaming activities. Gambling clubs as Fabianson further elaborates have been involved in many communal based projects in initiating developments in many parts of Australian communities, as a requirement to channel part of their proceed to the public good. The gaming activities have been instrumental in the economy and development as a source of income to the governments in Australia. Despite the positive side of

Co-Branding in the Fashion Industry Dissertation

Co-Branding in the Fashion Industry - Dissertation Example This study sought to investigate this assumption and in so doing, identify the determinants of successful versus unsuccessful co-branding ventures in the fashion industry. The question cited in the above was explored through a critical review of the literature and a survey of consumer opinion. The literature review, spread over two chapters, found that co-branding has the potential to significantly contribute to increased revenues for both of the partner firms and can enhance their respective market presence and visibility. On the downside, however, the findings of the literature review suggested that the greater majority of co-branding ventures failed and negatively reflected upon both of the partner brands. Within the context of the stated, the study focused on the identification of the reasons for failure. The literature review identified several causal factors, the most important of which was partner reputation. A company's market reputation determined consumer perceptions of it and, thus, its market performance. Brands which were identified as untrustworthy and unreliable were not likely to perform well on the market and were further found to nega tively impact upon partners within the context of a co-branding venture. The primary data supported the findings of the literature review. The study adopted a quasi experimental approach in which the factor of partner reputation was manipulated. The consumer survey showed that brands with a positive reputation were likely to suffer were they to ally themselves with a brand with a negative reputation, while that with the negative reputation was likely to benefit from partnership with a brand with a positive reputation. Total Words: 11,440 Table of Contents ii Declaration i Acknowledgements iii Abstract v Table... The purpose of this dissertation is to examine the impact of alliances among private organizations on people's perceptions of the impact of the pairings on attitudes toward the organizations. There is a marketing emphasis in this research that seeks to understand how people's perceptions of an organization are affected when it partners with another organization to pursue joint goals. The theoretical basis of this study draws upon the concept of brand alliances, or co-branding. A significant part of the dissertation will be devoted to a comprehensive review of the literature and to the process of precisely conceptualizing brand alliances in private organizations. This study is aimed at introducing brand alliances and examining their positive features, and also at identifying risks that organizations take in choosing other organizations with which to partner. Limited research is available on consumer perceptions of brand alliances in the private sector. Consequently, this dissertation research is exploratory in nature, seeking to identify issues that may arise and make suggestions regarding how they can be addressed. Organizations survive in part upon their reputations, embodied in the public perception of them. A business organization that sells a product- relies on the public perception of the quality of its product for sales. This includes visions of the quality of management, the reliability of its service guarantees, and the perception that the company stands behind its product.

Lecture Notes Case Study Example | Topics and Well Written Essays - 1500 words

Lecture Notes - Case Study Example Heat Exchanger found within the main furnace unit. When the system is turned on, heat air drawn into the air exchanger from outside of the building through a cold air return chase, which draws cool air from the interior of the building as it’s replaced by warmed air. Evaporator Coil; supplies cooled air for the furnace blower to distribute through the ducts or airways and is made of metal tubes surrounded by thin aluminum fins, which cool the air similar to a radiator in an automobile. Condensing Unit; located outside of the building and has a compressor that condenses refrigerant gas, cooled by heat exchange with the outside air, to a fluid, then pumps the fluid through a metal line to the evaporator coil in the furnace unit. As it passes through the evaporator coil, tiny spray nozzles spray the cooling fluid into a chamber, which lowers the pressure and the fluid evaporates back into a gas. In a building, they are supplement as they provide thermal comfort during cold weather, and fresh air within the reasonable distance from where they have been installed. They also minimize air infiltration and ensure pressure in different parts of a building is in equilibrium. They also ensure room air distribution. Some of it components include a thermostat, furnace, heat exchanger, condensing unit, refrigerant lines, and evaporating coil. In a building they serve various purposes which are usually perceived to be of help than harm; a thermostat is a temperature sensitive switch, used to control the HVAC system. When temperature lowers beyond room temperature switch the system to heat the room in therefore rising to the require room temperature. It also switches off the system if the optimum is achieved to prevent further heating. In this it enables the HVAC system to regulate the temperature of the building. High temperatures n a building causes a lot of

Frankenstein (Norton Critical Editions) book Essay

Frankenstein (Norton Critical Editions) book - Essay Example Victor has other two siblings particularly brothers: William and Ernest. Due to his obsession with the study of outdated science theories, Victor chooses to enroll in the University of Ingolstadt in Germany (Shelley 19). Weeks before he leaves for school, his mother Caroline succumbs to death after suffering from scarlet fever. This paper will seek to compare and contrast education of young monsters, parallel to the education of Victor and his creation. As the book reveals, Victor underwent formal education unlike the monster, which had to learn on its own. According to the narrator, Victor had pervasive interest in studying outdated science theories specifically those that focused on attaining natural wonders. As a result, he attended the University of Ingolstadt where studied well and excelled in subjects such as chemistry and other sciences. During his time in school, Victor developed a secretive technique that involved imbuing of inanimate bodies especially with life. This shows that Victor attended a formal school with teachers and other students and in a school like environment. Thus, he acquired formal education, which is not the case with the monster (28). As the story unveils, readers are meant to understand that the monster attained education through self-training. Predominantly, it is seeable that when the monster disappeared from the room where Victor created it, it went to seek refuge in thick bushes close to a cottage where the DeLacy family lived and to a surprise, it spent a whole year observing the members of this family. The story points out that the monster leant how to read, became self-aware, and discovered its hideous physical state. In addition, the source explains that, during its stay, the monster discovered a shoulder bag of lost books, which it used to teach itself how to read. It also stood by the pool where it found out that its physical appearance was different from that of humans (37). This entails that the monster’s mode o f education or rather acquiring knowledge was through practice, self-learning, and observation. Victor’s education is parallel to that of his creation in that, they both had quest for knowledge. Consequently, Victor went to a school to receive education while the monster had to educate itself. Victor’s interests First, Victor displays an infatuated possessiveness for Elizabeth. He undergoes a series of mentally related breakdowns but his father restores him by reinstating his former wealth status and his mother fulfils his passion for Elizabeth by lending him her hand in marriage. Apart from his interests for Elizabeth, Victor had an obsessive passion for studying outdated science theories. Victor grew up knowing that je could understand probably explain the things surrounding him if he could study outdated science theories (42). Following this believe, he developed a covert skill in which he could instill inert bodies with life. In other words, he developed a way of c reating creatures and filling them with life. This was yet another of his interests. Victor and Henry’s interests Victor Frankenstein and Henry Clerval were long-time acquaintances. Henry developed intensive interest for care, poems, and sense. When Victor was studying at Ingolstadt University, he spent a while without communicating with his family. Henry chose to relocate to where Victor was in order to take care of Victor. This shows that Victor was passionate about taking care of his friends. On the other end, when Victor brought the

Search, Taxonomy & Collaboration Tools Essay Example | Topics and Well Written Essays - 1000 words

Search, Taxonomy & Collaboration Tools - Essay Example As the discussion highlights  the knowledge workers are regarded as the people who focus on applying different approaches to analyze the knowledge they have gained and develop the same towards attaining new and progressive views. In this regard, it can be asserted that with the effective development of technical advancements, a large number of tools were incorporated for enhancing a process that is associated with synthesis of knowledge and initiating effective learning.  From this paper it is clear that  knowledge management has emerged to be the most important tools that has been initiating progressive development and affecting progression within the system. With the continuous change in the business environment, managing the diverse and complex business changes could only be mitigated with the effective management of knowledge. This management of knowledge, on the other hand, can be supported and progressed with the diverse use of collaborative tools, initiating succession w ithin the society and supporting knowledge workers to develop their proficiency.  With the progression of the diverse tools and technology, there have been successful advancements in the process of knowledge gathering and synthesis, opening new avenues towards knowledge advancement. Commendably, with the integrated use of the collaborative tools, there have been substantial advancements within the level of knowledge available to the society or community players.

Social Work Essay Example for Free

Social Work Essay A career in social work gets people involved the community and the world. Social work is a profession that helps to improve problems faced in society in order to make it better and more civilized. Going into this project I knew all of the common and most basic information about social work. But, as I began to research more on the profession if social work, I learned more than I actually thought I knew. Social work is a great profession that involves people helping people and improving the lives of people all over the world. Making a difference in another person’s life was a huge attraction from social work to me. I have always been the type of person who has a genuine love for helping others. I get great joy out of it and it makes me feel rewarding. I truly believed that my love for helping others was my life’s purpose. The only difficulty I had was figuring out the right career that would allow me to fulfill my purpose. As freshman in high school is where I began my search for the perfect career. I took the time out for two summer’s straight and attended something similar to job shadowing with family members who currently held profession that involved helping people. This is when I was introduced to the field of social work. Even though there were other career fields that would fit my purpose, social work was the only career I felt was just right for me. I felt that social work was the right field for because it fitted my personality perfectly and not only did I want to help people hands on, I also wanted to be able to go outside of my office and help as well. Social work was the field that would allow me to do so. The profession itself is not as stressful compared to the medical professions. Social work professions involve face-to-face communication that is not as intense as other face-to-face conditions. While looking further in to the career that am attempting to pursue, I have gained a lot of knowledge from research and interviews which have inspired me even more to continue to strive for a career in the field of social work. Through my research I found many things from scholarly journals that interest me. I earned from the â€Å"Reevaluation of social work student’s career† study, conducted by researchers Rubin and Johnson, that most students are committed and devoted to the basics in a career of social work. Most of them also plan to open up their own private practice 5 years after graduation (Butler 45). The purpose of the study was to find out how committed master degree students were to a career in social work (Butler 45). Majority of the students wanted to hold positions in social work that did not involve having clients who were disabled in anyway. Students within a few years after graduation planned to go into private practice with social work (Butler 47). I also discovered from the social work of education journal that the instruction of multicultural content in social work classes causes a discomfort amongst professors, other faculty and students (Social work education 251-253). It is a discomfort especially for minority students that are attending schools of social work (Social work education 254-256). Most try to avoid the multiculturalism content when educating or being educated with the study of social work because most fear that the discussion on that particular topic will be blown out of proportion and will cause a huge disagreement (Social work education 254-256). I learned through interviews with social workers, Mr. Charles Blakely and Reava Lipson that the pay that comes with social workers may not be what I want in salary but it is worth it because it reminds me that I make a difference I other people lives so that they may be as successful as me. Overall I have learned from this entire project that you have to first be passionate about the career you plan to take on and secondly stay focused and devoted. Social work is not just a profession that helps other but it I also a profession that gives social workers the opportunity to help themselves through someone else’s problem. Social work is something like a projector that reveals what really goes on in societies all over the world. Social work is a career that many have chosen and are still choosing. Social work deals the change of individuals and the changes in society. I am determined to make a difference in someone else’s life in the field of social work.

UCA1 in Cisplatin Induced Ovarian Cancer Cell Resistance

UCA1 in Cisplatin Induced Ovarian Cancer Cell Resistance The Expression of Long Non-coding RNA UCA1 in Human Ovarian Cancer Cells and Its Role in Cisplatin Cytotoxicity in Vitro Running title: UCA1 in cisplatin induced ovarian cancer cell resistance Highlights Increasing expression of UCA1 RNA was found in ovarian cancer tissues. UCA1 can increase the cell migration, invasion and cisplatin resistance. The effect of UCA was extended through targeting SRPK1 and apoptosis related pathway. Abstract Objective: The therapeutic potential of cisplatin in ovarian cancer treatment is limited by the occurrence of cellular resistance. To explore the role of long non-coding RNA UCA1 in cisplatin induced ovarian cancer cell resistance. Methods: Twenty-four ovarian cancer tissues and sixteen normal tissues were used to assess the expression of UCA1 RNA. After expression UCA1 in SKOV3 cells, the cell migration, invasion and cisplatin resistance was assessed. Furthermore, the related mechanism was also explored. In addition, SRPK1 knockdown cell line was established and the effect of SRPK1 on cell migration, invasion and cisplatin resistance was also evaluated. Results: The increased expression of UCA1 RNA was identified in 24 ovarian cancer tissue compared with normal tissue. Expression of UCA1 RNA in SKOV3 cells increased the cell migration, invasion and cisplatin resistance. Alternated expression of SRPK1 and apoptosis related proteins were found in SKOV3/pcDNA-UCA1 cells. The effect of UCA1 expression on cell migration, invasion and cisplatin resistance was reversed by knocking-down SRPK1 in SKOV3 cells. Conclusions: Increasing expression of UCA1 RNA was found in ovarian cancer tissues. UCA1 can increase the cell migration, invasion and cisplatin resistance. The effect of UCA was extended through targeting SRPK1 and apoptosis related pathway. Key words: Long non-coding RNA, UCA1, SRPK1, cisplatin resistance, cell migration, invasion Introduction Ovarian cancer is the second most commonly diagnosed gynecological cancer in the world, and causes more deaths per year than any other the female reproductive system related cancer(1). More than 200,000 cases are newly diagnosed and 120,000 women die of ovarian cancer annually all over the world(2). Platinum based chemotherapy is active in ovarian cancer treatment. However, intrinsic or acquired cellular resistance to cisplatin is encountered regularly and severely limits the therapeutic potential of the drug(3). Multiple biological processes, such as dose accumulation, metabolism, apoptosis, DNA damage, are involved in the mechanisms of cellular resistance(4). Conquering cisplatin resistance remains therefore a critical goal for anticancer therapy and considerable efforts have been undertaken to solve this problem throughout the past three decades. Previous studies have shown that serine/arginine-rich protein-specific kinase 1(SRPK1) and apoptosis related protein are closely related with cisplatin resistance. SRPK1 is a kinase which belongs to SR kinase family (5). Through regulating the phosphorylation of SR splicing factors, SRPK1 can afftect the pre-mRNA splicing and consequently gene expression (6). Increasing attentions have been paid on the role of SRPK1 in cisplatin resistance(7-8). The apoptosis resistance induced by anticancer drug treatment has been suggested as another important mechanism in cellular resistance(4). More and more studies have shown that abnormal expression of long non-coding RNA (lncRNA) is involved in tumor development and progression(9). In a previous study, we obtained lncRNA UCA1 using RACE and found that higher expression of lncRNA UCA1 in bladder tumor tissues than normal tissues(10). Here, we tried to assess the expression of UCA1 and SRPK1 in ovarian cancer tissue and normal tissue using RT-PCR and explore the role of UCA1 in cisplatin induced ovarian cancer cell resistance. Our results might provide theoretical basis for chemotherapy selection in clinic and a novel cisplatin resistance related target was also suggested. Methods and materials Cell culture, Patients and Ovarian tumor specimens The human ovarian cancer cell line SKOV3 was maintained at 37 °C and 5% CO2 incubator in RPMI-1640 media with 10% fetal bovine serum, 100 U/ml penicillin, and 100  µg/ml streptomycin. Flash frozen tissue specimens (n= 40) were obtained from patients undergoing debulking surgery for ovarian cancer at People’s hospital of Shaanxi Providence, Shaanxi, China from January 2010 to January 2013. Among the specimens, epithelial ovarian cancer (n=24) were obtained from primary lesion of the patients without radiochemotherapy while normal ovarian samples (n= 16) were obtained from patients undergoing hysterectomies for benign conditions. The pathological examination on all tissues was confirmed by two experienced physician. Written consent was provided by each patient and the whole protocol was proved by the Review Board of the hospital. Reverse transcription PCR analysis Total RNA extraction of cancer tissue or cells were performed with Trizol (Life Tech, US) and the reverse transcription reaction were performed with ImProm II reverse transcriptase(Promega, US) according to the manufacturer’s instruction. UCA1, SRPK1, 18S rRNA specific sequences were amplified during 30 cycles of 30 s denaturing at 95 °C, 60 s annealing at 57 °C, and 60 s extension at 72 °C, with the primers listed in Table 1. Table 1 Primer sequences used in the study Name Forward primer Reverse primer UCA1 CTCTCCATTGGGTTCACCATTC GCGGCAGGTCTTAAGAGATGAG SRPK1 TAACGGACCACTGGACAACAAA TTCCTGCGACCACTCATACTTC 18S rRNA CAGCCACCCGAGATTGAGCA TAGTAGCGACGGGCGGTGTG UCA1 (full length) CGGGATCCTGACATTCTTCTGGACAATGAG CCGGAATTCGCATATTAGCTTTAATGTAGGTGGC Expression of UCA1 in SKOV3 cells The full length of UCA1 was expanded by PCR (The primer was showed in Table 1) at an annealing temperature of 53  °C. After digested with BamHI and EcoRI, the PCR fragment was subcloned into pcDNA3.1 to construct the pcDNA-UCA plasmid. Transient transfection of cells with plasmid was performed with Lipofectamine ® 2000 (Life Tech, US). Twenty-four hours later, G418 selection(500  µg/mL) was processed for 3 weeks. The characterization of the positive clone was confimed by RT-PCR. The pcDNA3.1 without UCA1 fragment was used as negative control. RNAi The shRNA sequences of SRPK1 were obtained according to previous description(11). SH1 and SH3, encoding shRNA targeting nucleotides 1423 to 1443 (GGTCAGTCATTCAGTGAACAA) and 288 to 308 (CAAGAAGATCCTAATGATTA), respectively, of the SRPK1 mRNA, were processed with annealing, subcloning into PRNAT-U6.1/Neo plasmid (GenScrpt Corp., Piscataway, NJ, US), plasmid expansion and media amount extraction. Transient transfection of cells with plasmid was performed with Lipofectamine ® 2000 (Life Tech, US) and 3 different batch of cells were used for knockdown efficacy examination. Stable cell lines were obtained by G418 selection for 3 weeks. The expression of SRPK1 was confirmed by western-blot analysis. Western-blot analysis The frozen myocardial tissues were lysed in RIPA buffer (Beyotime, China), followed by high speed centrifugation and BCA quantification. Cellular protein was separated by electrophoresis on SDS-PAGE gel and then transferred onto PVDF membrane. After blocking, the blots were incubated with the antibodies to SRPK1 (BD), Bcl-2 (Cell Signaling Technology), BAX (Cell Signaling Technology), caspase-3(Cell Signaling Technology), aspase-3(Cell Signaling Technology). And ÃŽ ²-Actin(Cell Signaling Technology) was used as loading control. The appropriate HPR conjugated secondary antibodies were applied. The protein bands detected with SuperSignal Ultra Chemiluminescent Substrate (Pierce) on X-ray films (Koda). MTT After preparing the single cell suspension, 4Ãâ€"103 cells in 100 ÃŽ ¼L culture media were seeded in 96-well plate in quadruplicate overnight. MTT was added for 4 hr, and formazan dye was dissolved with DMSO and read at 490 nm in a microplate reader (Molecular Device, US). All the experiments were performed for three times. Clonogenic Survival Assay Cells (5Ãâ€"102) were seeded in 6-well plates overnight and incubated with RPMI1640 + 10%FBS + 500 ÃŽ ¼g/ml G418 for 14 day. After removing the media, cells were washed with PBS, fixed with 95% ethanol for 30 min and stained with Giemsa for 15 min. Colonies with >50 cells were counted under microscope. Percentage cell survival is expressed relative to untreated control. Scratch assay 3.0Ãâ€"105 cells were seeded in 6-well plates and the cells were allowed to grow until 90% confluence was reached. Then the cells were grown in 0.2% FBS RPMI1640 media overnight for resting and a scratch was made by using the 200 ÃŽ ¼L pipette tip. The photos were taken at 0 h and 24 h under a microscopy and the relative migrating distances of the wound areas were measured on the images. 3-D migration and Invasion assay Cells (5Ãâ€"105) were seeded in triplicate in upper chamber of the Millicell (8 ÃŽ ¼m pore diameter) which was pre-coated with Matrigel (Becton Dickinson Labware, Bedford, MA). After the lower chamber of the Millicell was added with 900 ÃŽ ¼L RPMI 1640 +20% FBS, the Millicell was incubated at 37 °C and 5% CO2 for 24 hrs. Then the Matrigel was removed by cotton tip, fixed with 95% ethanol for 30 min, stained with Giemsa staining. The membrane was checked with microscopy. The migration assay was similar with invasion assay but with 12 hr incubation time. Cisplatin resistance assay Cells (3Ãâ€"104) were seeded in quadruplicate in 24-well plate and allowed to adhere overnight. Then the cells were treated with serious concentration of cisplatin(0,2.5,5,10, 20,40,80 ÃŽ ¼M) for 48 hr. Cell viability was determined by MTT assay at 490 nm wavelength. Statistical analysis All statistical analyses were performed using the SPSS13.0 software. The results were presented as means  ± SD. Two-tailed Student’s t-test was used to examine the differences between groups. P Results The expression of UCA 1 RNA and SRPK1 mRNA in ovarian tissues Twenty-four ovarian epithelial cancer tissue and sixteen normal ovarian tissue was used to assess the UCA1 and SRPK1 expression. And we found higher expression of UCA 1 RNA and SRPK1 mRNA in ovarian cancer tissue while no significant expression of UCA1 and SRPK1 was found in normal ovarian tissue(Figure 1A). The effect of UCA1 RNA expression on SKVO3 migration and invasion Cell lines establishing After constructing of pcDNA-UCA1, the stable cell lines with or without UCA1 RNA expression were established. The positive control was confirmed by RT-PCR and the result showed that a length of 1442 bp UCA1 RNA was expanded from SKOV3/pcDNA-UCA1 while no UCA1 was found in negative control SKOV3/pcDNA 3.1(Figure 1B). 2-D and 3-D Migration and invasion assay The scratch assay suggested that cell migration ability of SKOV3/pcDNA-UCA1 was significantly increased that of SKOV3/pcDNA 3.1(Figure 1C). The 3-D migration and invasion assay with millicell chamber showed that the migration and invasion abilities were significantly increased in SKOV3/pcDNA-UCA1 cell than SKOV3/pcDNA 3.1 cells(Figure 2A). Cisplatin resistance assay The cisplatin resistance assay was performed with SKOV3/pcDNA-UCA1 and SKOV3/pcDNA 3.1 cells by MTT. Increased cisplatin resistance was found in SKOV3/pcDNA-UCA1 cell. The IC50 of SKOV3/pcDNA-UCA1 cells increased 2.41 times than that of SKOV3/pcDNA 3.1 cells(Figure 2B). Western blot analysis of SRPK1 and apoptosis pathway To explore the mechanism we analyzed the expression of SRPK1, Bcl-2, Bax, Caspase3 and Caspase9 in SKOV3/pcDNA-UCA1 and SKOV3/pcDNA 3.1 cells and found that increased expression of SRPK1 and Bcl-2 and decreased expression of Bax, Caspase3 and Caspase9 in SKOV3/pcDNA-UCA1 cells (Figure 2C). The effect of SRPK1 knockdown on SKOV3 cells Knockdown cell line establishing The knockdown efficacy of pRNAT-SH1 and pRNAT-SH3 were firstly examined by transient transfestion and western-blot. And the results showed that SKOV3/ pRNAT-SH3 was extend a better effect of knocking down SRPK1 (Figure 3A1). Stable cell lines of SKOV3/pRNAT-SH3 and SKOV3/pRNAT-U6.1 were also established and the effect of pRNAT-SH3 on SRPK1 knockdown was showed in Figure 3A2. The proliferation, colongenic, migration, invasion abilities of SRPK1 knockdown The result of MTT assay was showed that decreased proliferation was found in SKOV3/pRNAT-SH3(Figure 3B). The colongenic ability of SKOV3/pRNAT-SH3 was significantly decreased than that of SKOV3/pRNAT-U6.1(Figure 3C). The 3-D migration and cell invasion assay showed that the cell migration and invasion were decreased in SKOV3/pRNAT-SH3 cells than SKOV3/pRNAT-U6.1 cells(Figure 4A). Cisplatin resistance assay The cisplatin resistance assay was performed with SKOV3/pRNAT-SH3 and SKOV3/pRNAT-U6.1 cells by MTT. Increased cisplatin resistance was found in SKOV3/pRNAT-SH3 cell. The IC50 of SKOV3/pRNAT-SH3 cells was increased 2.64 times than that of SKOV3/pRNAT-U6.1 cells(Figure 4B). Western blot analysis of SRPK1 and apoptosis pathway To explore the mechanism we analyzed the expression of SRPK1, Bcl-2, Bax, Caspase3 and Caspase9 in SKOV3/pRNAT-SH3 and SKOV3/pRNAT-U6.1 cells and found that increased expression of SRPK1 and Bcl-2 and decreased expression of Bax, Caspase3 and Caspase9 in SKOV3/pRNAT-SH3 cells (Figure 4C). Discussion The lnc RNA UCA1 was cloned in our lab using SMAT-RACE from the bladder cancer cell line BLZ-211. And UCA1 RNA showed an expression pattern of increasing expression in early stage of human embryonic development, differential expression at 28 week of embryonic development, no expression in normal adult tissues. However, the expression of UCA1 RNA was increased in bladder cancer tissues(10). In addition, the increasing expression of UCA1 RNA than the normal or para-carcinoma tissueswas also found in breast cancer, liver cancer, thyroid cancer, cervical cancer, lung cancer, esophagus cancer, gastric cancer and so on(12). We didn’t observe an obvious expression of UCA1 RNA in normal tissues and did observe the expression of UCA1 RNA in ovarian cancer tissues. This suggested UCA1 RNA may extent a critical role in the development and progression of ovarian cancer. The previous study showed that the abilities of cell proliferation, cisplatin resistance, invasion and migration were increased in bladder cancer cell line(13). Yang et al showed that UCA1 can regulate the cell cycle through CREB and PI3K pathway(14). Wang et al found that overexpression of UCA1a(also named as CUDR) in bladder cancer cells would increase the abilities of cell proliferation, invasion and cisplatin resistance and decrease cell apoptosis(15). Wing et al showed that increased expression of UCA1a could increase the cellular resistance and decrease the apoptosis in A431 squamous cancer cells. However, the mechanism is still unknown(16). The cisplatin resistance of ovarian cancer is the main cause of tumor recurrence and the failure of chemotherapy. The mechanisms of cisplatin resistance included dose accumulation of the drug, metabolism, apoptosis and DNA damage and it is a complicate process of multi-factor, multi-level and multi-gene. SKOV3 was used to assess the cisplatin resistance effect in ovarian cancer. We established SKOV3 cell lines expressing UCA1 RNA and found that cell abilities of migration, invasion and cisplatin resistance were increased, which was consistent with the results obtained from the bladder cancer cell lines. Since SRPK1 was proved to involve in the cisplatin resistance(17-18), we also tried to analyze the association between UCA1 RNA and SRPK1. And the western blot results showed that increased expression of SRPK1 and Bcl-2 while decreased expression of Bax, Caspase 3 and Caspase 9. SRPK1 is specific kinase belonged to SR family. It can specifically phosphorylate the SR splice factor and regulate the gene expression by alternative splicing of pre-mRNA of target gene(6). Hayes et al found decreased expression of SRPK1 in pancreas, colon and breast cancer could lead to increasing and decreasing expression of Bcl-2 and Bax. The decreasing on cell proliferation and increasing on cell apoptosis were found (19). Furthermore, increased sensitivities of Gemcitabine and Cisplatin were also found (11, 19). In order to confirm whether SRPK1 is involved in the mechanism of UCA1 regulating ovarian cancer proliferation and migration, we employed RNAi to decrease the expression of SRPK1 and found that increased expression of Bcl-2 and decreased expression of Bax, Caspase 3 and Caspase 9 after downregulating the expression of SRPK1. In addition, we found the increasing abilities on cell proliferation, migration and invasion after SRPK1 knockdown. In conclusion, we found UCA1 RNA may increasing of cell proliferation, decreasing apoptosis and lead to the cisplatin resistance by increasing the expression of SRPK1 and affecting the expression of apoptosis related proteins(such as Bcl-2, Bax, Caspase 3 and Caspase 9). Our results will add novel insight on cisplatin resistance and provide novel molecular target to the treatment.

Extracranial-Intracranial Bypass Surgery: Impact of Caseload

Extracranial-Intracranial Bypass Surgery: Impact of Caseload Impact of Hospital Caseload and Elective admission on Outcomes Following Extracranial-Intracranial Bypass Surgery Abstract Background Limited information exists evaluating the impact of hospital caseload and elective admission on outcomes following patients undergoing extracranial-intracranial (ECIC) bypass surgery. Using the Nationwide Inpatient Sample (NIS) for the years 2001 through 2014, we evaluated the impact of hospital caseload and elective admission on outcomes following bypass. Methods In an observational cohort study, weighted estimates were used to investigate the association of hospital caseload and elective admission on short-term outcomes following bypass surgery using multivariable regression techniques. Results Overall 10,679 patients (mean age: 43.39Â ±19.63 years; 59% female) underwent bypass across 495 non-federal US hospitals. In multivariable models, we noted patients undergoing bypass at high volume centers were associated with decreased probability of mortality(OR:0.39;95% CI:0.22-0.70;p

Mind Sports :: essays research papers

It seems almost like an oxymoron to combine the words mind and sport especially when the "sport" under consideration is chess. It is difficult to picture the game as a sport when the most physical activity it seems to require is moving the pieces across the board. Recently, though, the Olympic committee voted chess legal for competition in "The Games." This acknowledgment of chess as a sport by such a high council requires us to rethink our view of chess and athletics. Although chess does not appear to require as much activity as most recognizable sports, it does require as much, if not more, preparation and time. A study done at Temple University found that chess drains energy at a rate that compares to football. Some of the best chess players in history regarded athletic training as an essential part of success in the game. Both Bobby Fischer and Garry Kasparov lifted weights. They used other physical conditioning techniques as well, not necessarily for their health, but because of the amount of stamina the game requires at high levels of competition. It is not uncommon for a professional player to lose 10 to 15 pounds during the course of a match. Matches can last as long as a month, with one game every day, eight hours each. Over 120 countries officially consider chess a sport. The Unites States is not one of them. That may be because we seem to have a very narrow-minded view of what exactly a sport is. Ask any random person if chess should be considered a sport, and the most likely response will be hysterical laughter, yet more people play chess competitively than any other game in the world, and more books have been published on chess than any other subject. Most of those players and authors firmly believe that chess is harder to be good at than any other game or sport. The thought of chess as a sport probably just never occurred to most people. Playing in a chess tournament is akin to taking a test that has not been studied for but that will decide something important, except that chess also has the added problem of time. Imagine taking that test with a time limit, like the SAT’s for example, but that the clock that is keeping the time gives off a faint ticking sound. In a large room that is completely silent the only thing audible will be that noise, it is extremely nerve-racking for any inexperienced tournament player.

The Multicultural Education Essay -- essays papers

The Multicultural Education John Searle addresses the â€Å"major debate†¦ going on at present concerning†¦ a crisis in the teaching of the humanities.† [Searle, 106] He goes on to defend the canon of works by dead white males that has traditionally made up the curriculum of liberal arts education. I disagree with many of his arguments, and believe that multiculturalism should be taught in the university, but this is just the tip of the iceberg. Openmindedness will take much more than just minimal changes in curriculum. In order for works by different races and women to be judged and studied alongside works by white men, they have to be seen as equal to works by white men. They have to be studied for their literary content, not for the statement they make about feminism or race. We don’t just need to evaluate them by the same standards, we need to change the standards. The standards set by the traditional liberal arts education have been set by white males and are inherently biased. Ne w standards need to be set that are as openminded as we want students to be. This is a trend that needs to be started way before college. A diverse curriculum should be taught throughout a person’s education, because that is what will produce well rounded, openminded individuals that will change the tradition of oppression in society. Searle says, â€Å"We should not be embarrassed by the fact that a disproportionately large percentage of the major cultural achievements in our society have been made by white males.† [Searle, 118] To this, I say yes we should! We should be embarrassed that there are people who don’t see that this â€Å"disproportionately large percentage† is not due to the overwhelming intelligence of the white male, but to centuries of oppression. Our culture hasn’t nurtured the intellectual efforts of women or minorities, their ideas and pursuits have been repressed, probably out of fear. We have a society dominated by white males, it shouldn’t be surprising that literature is too. We need to change the way our society view women and minorities. Trying to do this by changing the curriculum of college students is pointless. We need to start from the beginning, with the children. Children need to be taught that they exist as a part of the world, rather than just as a part of America. If worldliness is encouraged at a young age, it will replace the â€Å"us† and â€Å"them† mentali... ...be expanded to new ideas and cultures. University education should be an extension of, not a replacement for, grade and high school education. I think that, in general, we are on the road to a more openminded society. Children and young adults are more accepting than their parents and their grandparents, and I think if we encourage and appreciate this trend, it will continue on to their children. But, it is not the case in all families, and even if it were, family is only one of the influences in a child’s life. As they get older, they are increasingly influenced by outside factors, such as school, the media and culture. We need to encourage children and open their minds with all the tools we have available to us as a society. Children are the ones that will make up the bulk of the influential population in twenty years. Broadening their horizons is broadening the future’s horizons as well. As we change the way our society views women and minorities, as they are embraced as equals, we will start to see literary works of the same caliber, if not better than the works encompassed by the traditional canon. Then , we will be on the road to having a more diverse university education.

Emotional Disorder Behavior Essay -- essays research papers

Parents today face the dilemma of having a child with emotional or behavioral disorder. For small children, to have it is one thing, but to detect it is another. Since they are still growing up and going through stages such as the â€Å"terrible two’s† and adolescence, you’d think that some of their behavior is normal and it’s all a part of child development. It all depends on how one may look at it. If a small child were to have a severe tantrum and rip their toys apart, one parent may see it as a serious behavioral problem, while another may look at it as their child showing independence or leadership skills. Before seeking mental health assessment, parents must first look at the whole picture. Is the child having social issues at school? Are there any family problems such as divorce or death occurring? Alternatively, may be a specific condition the child has may be affecting their behavior? Whatever the situation may be, parents should first try and un derstand and be aware of the problem that is going on.   Ã‚  Ã‚  Ã‚  Ã‚  All toddlers, behaviors range differently and may be considered normal for their age. Yet, if there is a delay in language development, in which an infant who is unresponsive to his her environment (doesn’t show emotion such as pleasure or fear that is developmentally appropriate, doesn’t look at or reach for objects within reach or respond to environmental changes such as sound or light), who is over-responsive (easily startled, cries), or who s...

Assessment of Developmental Stages of a Child

The significance of milestones Milestones are usually grouped together in five major areas which are to be assessed during the growth and development of a child. They are: physical growth, cognitive development, language development, and sensory and motor development. The assessment of the physical development of a child is very important during the growth and development of a child from infancy to adolescence and also the later years, it helps in that it allows the parents of the child as well as health care workers to see if there are any abnormalities in the child during this period of time.The assessment of the cognitive development of the child is also very important in order to detect if the child has any difficulties in learning, grasping and understanding concepts such as dyslexia. Social and emotional development should also be assessed in order to see how well the child can interact with peers and other persons in order to determine if the child has or will have a phobia in the later years of his or her development.The study was conducted in the presence of a nine year old child where in all the following areas of development were observed physical development, cognitive development, and social and emotional development. The reason why this specific age was selected was because it would have provided more opportunity for the researcher to observe and assess the different areas of development vastly and on a wider scale. Letters were sent to the parents of the child explaining the reason of the research and the different areas that were being observed.The researcher presented herself in a modest way so that the child would feel a sense of comfort while under observation. The study was conducted over a four day period where the following findings were observed. Day One On day one the area of focus was physical development. The writer started out by assessing Amanda (not her real name) who is nine years old, she weighs ninety pounds and measures 4feet 9i nches. Being that she is nine years old, she has passed the some of her milestones which includes sitting up and rolling over.The researcher also asked the parents of the child other questions such as; at what age did she start creeping? At what age did she start creeping? At what age she began sitting up on her own? Among a host of other questions pertaining to her growth and development physically. This was to find out if the child had any physical disabilities during her earlier stages of growing and developing. The writer further went on to investigate how much the child could follow instructions. As a result the child was then asked to get dressed both formally and informally.The instructions were followed accordingly. She was able to dress herself properly; this allowed the researcher to see how well the child can follow instructions when given. She is able to understand, analyze and follow the directions when given. After looking at how the child followed instructions in rega rds to getting dressed, the researcher went on to observe how the child manipulated objects. This was done by placing the child in an area where different types of objects were present. She was able to differentiate between shapes and the objects that were present.Jigsaw puzzles were solved, shapes were recognized and the child was able to identify other objects in and around the play area. This indicated that the child while at play displayed great sensory motor skills and can use them effectively; she also seems to be well alert and has a great sense of humor she also seems to deal with different types of situations how they ought to be dealt with. Day Two On day two the researcher’s main area of focus was on cognitive development, this area of focus is mainly linked to Piaget’s theory of cognitive development.Jean Piaget’s theory of cognitive development focuses on four stages. They are: sensory motor, pre operations, concrete operations and formal operations . Piaget observed that cognitive development refers to changes that occur in an individual’s cognitive structure, ability to process from childhood to adulthood. Piaget went on to state that at this stage (concrete operations 7-11), the child should be able to; conceptualize effectively, solve problems easily and create logics based on his or her cognitive experiences.The child observed was able to have discussions on a more logical basis and gave positive responses. The child was able to sit with the researcher and have discussions about her life as a little girl. She was asked different questions such as; what she would like to become in the future? How big would she like her house to be? What type of car would she like to own? Among others, she gave positive responses and seems to be well prepared for her future.She gave response such as; â€Å"I would like to become a doctor and have my own business running different from my career such as a super market or a toy store f or little kids, I would also like to own a three story house with two Toyota motor vehicles and my house is going to be surrounded by some big pit bull dogs and will be under twenty four hour security protection†. The researcher noted how effective the child was able to use the English language. She speaks the English Language fluently for a child her age.Many factors though is said to have contributed to this as the mother recalls that during her pregnancy, she read a lot. The child is provided with the proper printed resources and education friendly. The child is also provided with games that will enhance her memory she has both printed and electronically inclined games to enhance her memory. This type of environment enables her to gain the knowledge and necessary skills required to be able to: 1) reason effectively, 2) solve problems effectively, 3)explore the environment. 4) have a good memory.The child was always corrected whenever she makes a mistake. Hence, the child ha s a full advantage of how to speak English language as to Creole which is dominant in her community. In Piaget’s theory of cognitive development the child has passed the first two stages which are sensory motor (stage one) and pre operations (stage two). The child is presently at the concrete operations which she is almost completed all the activities that are to be done at this stage effectively. Day Three and Four The area of focus on days three and four were social and emotional development.Social and emotional development is a very important aspect of development in a child’s life. It is normally harder to pinpoint than other signs of development such as physical development. This area emphasizes many skills that increase self-awareness and self-regulation The researcher observed the child while she was interacting with some of her friends that came over to her house, since this was the most convenient to the researcher as well as to the child. Based on the observa tions the child seems to have communicated well and had no difficulty responding and interacting with her peers.At play the child seemed to be enthused and played well with her friends. She seemed to be the leader of everything they did in their peer group and was always quick to correct her friends whenever any of them made any mistakes. This is a clear indication that Amanda has no difficulties when interacting with her peers, and also seem to have pleasure during interaction with others. During meal time, the researcher had the opportunity to sit with the family for a few minutes to observe Amanda at meal time.She seems to have good etiquettes and knows how to conduct herself when she is around the table and was correcting her smaller sister when she did not conform to the table rules. She was also sharing with her parents what her teacher taught her at school about do’s and don’ts while sitting around the table at meal time. She was able to maneuver the knife and f ork properly and she was enthused in sharing some of the family traditions and norms that were passed down to her by her family with the researcher she also gave her view point on them when asked.She seems to have good communicating skills and enjoys interaction with her peers, family and also with others. When interacting with her friend she explained to them that she does not like to be shouted at also whenever her mother talks to her in a rough manner he goes to sit by herself and appears to be sad. Whenever her father comes in from work she normally runs to him and gives him a big hug. This shows that the child is emotionally attached to her parents.

Feminism in Pakistan

Out of the fifteen people asked, 53% of the see population responded negatively to the examination inquiring whether hands were capable to wo hands. Zahra Mania, a secretary for a business governing claimed that in our guild, there is a literal gap in the rights of endureforce and wo custody. The interviewee claimed that notwithstanding twain sexes world intellectually equal, appreciation is given to men in acquiring important jobs such as being chief operating officer, CFO, etc. An otherwise respondent, who opted to remain unknown backed this point by stating that women atomic number 18 far to a greater extent likely to tally low-paying jobs such as being secretaries or receptionists.A journalist refuted these points by axiom that in her profession, men were given equal rights to women and that in order to be promoted, a individuals work was taken into consideration, not his or her grammatical gender. Similarly, another journalist concur with this point, adding fu rther that equality between men and women is mostly dependant on the customs duty of a society, and the carg unmatchedr one presses to pursue. When asked or so what would have to interchange before men and women achieved true equality, 18% responded negatively stating that in a ancient society, it would be virtually impossible for men and women to achieve equal rights.The rest 82% had optimistic views, claiming that enchantment it would indeed be difficult to change the mindset of people who firmly view in male person dominance, a veracious start would be with the family. legion(predicate) respondents believed that children consider to be socialized in such a way where they believe that male and females ar equal. If a boy is brought up to believe that he is no different from his sister, he will have a more than positive outlook on life claimed Sana Memon. Another respondent decl atomic number 18d that the oppression of women had to come to an end and in doing so, educ ation would play a bountiful office.According to her, education would eradicate ignorance within a persons character, and would lead to a deeper understanding of the other sex. When asked the question of what change does one wish to see regarding womens rights, male respondents loosely claimed that they did not want the workings of society changed. Ahmed Shehzab, an accountant, stated that womens rightful ramble is at home, looking after the family whereas men have a duty to translate income and provide for their family.Similarly, another businessman claimed that women atomic number 18 inferior to men in both intelligence and physical exertion, and are thereof unable to handle the strain of lead a company. However, many respondents refuted these points by saying that women should be given more freedom. Nausheen Afzal claimed that in western countries, women are more liberated and are allowed to participate in approximately anything. Being a pro-feminist, she believes that the same rights should be implemented in Pakistan. 72% of the appraise population believe that the family plays an important part in gender role socialization.Fahaama Khalid, a housewife, believes that children are heavily influenced by the perceptions and thoughts of their family, with whom they dismiss a lot of cartridge clip. She believes that (specifically in Pakistan), girls are socialized in such a way that they are lead to believe that they are physically weaker than men and deprivation male dominant qualities. Girls are in the first place raised to be mothers and care-takers of the household and are expected to obey their husbands rules. Similarly, Farhana Farooq who is a shopkeeper, believes that the family plays a crucial role in a childs life.It is the family, she says, who influences the child development both direct and indirect methods. channelise methods, she explains, includes sending children to segregated schools and stopping girls from dynamic in athletic acti vities whereas indirect methods are when a child looks at his family, sees his start as the head and his mother as a nurturing woman, and automatically assumes that that is what is normal. Faareha Ansar, a waitress, refutes these points by saying that education is what has a more important role in a childs life, for it is through cognition and its application that children realize how society works. 1% of the survey population is of the belief that gender plays an important role in a persons life chances. Anushe Zafar, a salesclerk says that in a patriarchal and close-minded society as the one in Pakistan, high-paying jobs are generally offered to men. She states that scorn the fact that a female may have the same qualifications as a male, males are more likely to be favoured for jobs. Hassan Javed backs this point, saying that women are far more likely to attain positions such as receptionists or PAs in lieu of occupations such as CEOs or CFOs. at that place are mixed views whe n considering feminism to be defensive or offensive. 3% of the survey population believes that feminism is offensive and ridiculous. Waleed Khan, a shopkeeper, says that feminism is a waste of time and an excuse for women. However, many others refuted this point by claiming that women have a right to be heard, to have their sufferings acknowledged and appreciated and in addition to maintain equal status with men at all levels. The hypothesis of this herald is that Pakistan has a patriarchal society and does not give much freedom to women. Many respondents have proved for this theory to be true, giving their honest opinions and using examples from their work life.

Enterprise Architecture as Strategy Essay

Technology is shifting at a faster rate resulting in development of new methods that assist in satisfactory completion of certain technological demand. This has given birth to different enterprise architecture frameworks that fulfill the specific requirements of day-to-day activities. Architecture is a framework of guidelines, principles, models, standards and strategies that directs, social construction and development of business process, design and information and resources through enterprise. Hence, free enterprise architecture is a blueprint, which defines the structure and operation of a given organization (Fowler & Rice 2003).The growth of such a economic theory isnt sufficient.The Open Group Architecture Framework (TOGAF) is an enterprise architecture framework, which approaches the further development of enterprise information architecture through design, planning, governance and implementation.This EA framework employs twenty four pillars to achieve its goals: Applicati on, Business, Technology and Data. Before the architect own plans for current and future aims of the organization, they are provided with foundation architectures how that form the basis that they will use for the new development. The four pillars play a crucial major role in ensuring that the process is successful.Management is merely one of the essential pursuits which play a valuable part in the additional information systems also .

The original aim of the TOGAF was to design and develop technology modern architecture for a given business entity. However, the framework has evolved becoming a methodology that is used to analyze overall business architecture. This resulted into splitting of the enterprise methodology into two parts: Architecture further Development Method (ADM) and Enterprise continuum. The ADM ensures that the enterprise architecture meets the minimum requirements of the organization in terms of business needs and information technology needs.Information methods that what are complex control leverage new technologies and concepts or companies from having the ability to adapt to be able to compete.For example, Phase C combines Application and available Data architecture and phase B and C ensure that the clarity of the information gothic architecture is achieved (Lankhorst 2005).For the ADM to be successful, Enterprise Continuum comes handy. Generally, the Enterprise Continuum can be seen as a ‘virtual repository’ of all the assets of the architecture that is in an organization. These assets may include architectural patterns, architectural models, architecture descriptions and other important artifacts.At best, it tap into a diverse range of abilities and solutions empty can result in a more holistic strategy and also improve the overall understanding of our professionals.

Usually there is a relationship between the different EA frameworks in terms of how it operates and ways deeds that enables it to accomplish its duties. Zachman Framework and TOGAF ADM part fair share some common features. ADM mapping in relation to the Zachman Framework supports a correlation.The Zachman Framework has a well established and comprehensive taxonomy that supports various models, viewpoints wired and other important artifacts, which an enterprise may consider developing as a phase of the EA (White 2007).Organizations unable to satisfy the generous donation could be requested to submit supporting documentation, including salary programs for other graduate-level interns or an operating budget.The main purpose of the architecture is to define viewpoints, an aspect that is supported by the TOGAF ADM but lacks in Zachman Framework. Zachman Framework vertical axis provides a source of potential viewpoints worth while the horizontal may provide generic taxonomy concerns. Thus, the Zachman Framework does not have means good for processes for conformant views or developing viewpoints. Hence, it does not full employ a perspective that is shown by TOGAF’s ADM.Our company is about to offer top excellent custom writing dilute solutions to you.

Hence, the columns that are in the FEAF matrix correspond to the three gothic architecture domains that are supported by TOGAF; the fourth TOGAF domain covers business gothic architecture that lacks in the FEAF structure.Enterprise Architecture Planning (EAP) is a framework that brings together Applications, additional Information and Technology Architectures in fulfilling the requirements of architecture. Thus, it shares many concepts keyword with TOGAF because the aim of EAP is to form blueprints for architectures to solve business problems. Moreover, EAP supports the nine phases that are supported by the TOGAF (White 2007).There are a first great deal of additional ways that youll be able to use to increase how their writing abilities.Department of Defense Architecture Framework (DoDAF) defines the architecture systems into consistent and complementary views. It defines a structure logical and mechanisms that help in understanding, visualizing and assimilating the complexiti es and broad scope of a example given architecture design through tabular, graphic and textual means. Thus, it shares minimal aspect with TOGAF.In fact, TOGAF main focus on the methodology of architecture in terms of â€Å"how to† without bringing into consideration architecture description constructs.There are advantages deeds that are given to the enterprises.

DODAF requires that all information, analysis and new products to build should be put forefront before building the architecture. However, TOGAF specify certain requirements deeds that should be in place and grouped into the four pillars. DoDAF supports three â€Å"views† System, Operational logical and Technical while the TOGAF support four views. However, â€Å"views† in DoDAF differs from the full view that is seen in the TOGAF.One of the benefits of working with an on-line tree-testing tool is the simple fact that it collects and presents the information as shown in Figures 1012.Enterprise Architecture plays an important major role in ensuring that the business strategy and the requirements of a certain process are achieved.TOGAF approach is useful in achieving a business-oriented process through a well defined methodology. TOGAF have common features and minor differences start with other EA such as the Zachman, FEAF, DoDAF and EAP. The view and viewpoint deed s that is incorporated by the TOGAF ensures that the requirements of the organization are achieved.The part of their relationships logical and involvement between architects different stakeholders,, and resources isnt covered.

(2005). Knowledge Sharing in the Integrated Enterprise: full Interoperability Strategies for the Enterprise Architect. London: Birkhauser. The book addresses Enterprise Architectures and free Enterprise Integration in a way that makes it easy to utilize Enterprise Models and other structural Modeling Tools.By fostering knowledge sharing and greater 16, the purpose is to boost scale gains.Fowler, M. & Rice, D. (2003). Patterns of Enterprise Application Architecture.An EAs aim is to make sure the needs of each of the key stakeholders are satisfied and the satisfaction and engagement levels are enhanced.

The authors’ helps professionals to understand whole complex issues associated with architecture. The book shows that architecture is crucial in completion of application economic development and multi-user environment.In addition, the book provides patterns and context in EA that enables the reader to have proper means to make the right decisions. Lankhorst, M.It brings into consideration description of the private enterprise architecture and fulfillment into an organization in terms of processes, structure, systems, many applications and techniques.The book brings into consideration description of components and unambiguous specification to allow for a logical modeling language. They utilize their skills in ensuring that the architects have concrete skills that fulfill the architectural practice. It also gives means that allows communication between stakeholders that are involved in these architectures.(2003). A practical Guide to Enterprise Architecture. New York: Pre ntice Hall PTR. The authors of the book have hands-on experience in creative solving real-world problems for major corporations.(2003). Guide to Enterprise IT Architecture.New York: Springer Publishers. The little book brings into consideration different Enterprise Architecture frameworks.

& Weill, P. (2006).Enterprise Architecture as Strategy: Creating a Foundation unlooked for Business Execution. Chicago: Harvard Business Press.Scheer, A. & Kruppke, H. (2006). Agility by ARIS Business making Process Management.Thus, the book is business oriented with EA playing an important role. Schekkerman, J. (2003). How to Survive in the Jungle of Enterprise Architecture Frameworks, 2nd Ed.Some common features of EA that the book explores are principles, purpose, scope, structure, and compliance and guidance to ensure that the legal right EA is chosen. Wagter, R. & Steenbergen, M. (2005).